Serving the Lesbian, Gay, Bisexual and Transgender community since 1994

The second-oldest LGBT organisation in South Africa, OUT provides stigma-free HIV, sexual health and other services to gay, bisexual and MSM communities. We also work to eradicate LGBT+ hate crimes and discrimination while assisting and supporting victims.


Developed by Dr. Chil-Yong Kang and his team at Western’s Schulich School of Medicine & Dentistry, with the support of Sumagen Canada, the researchers said that the vaccine “holds tremendous promise for success in the final phases of clinical testing now that the first hurdle has been accomplished”.

It is the only HIV vaccine developed in Canada currently in clinical trial, and one of only a few in the world.

This first phase of tests focused on the safety of the vaccine, while upcoming trials will assess the success of the vaccine in stopping HIV infection.

According to the researchers, initial results already suggest “a success of the Phase 2 human clinical trial, which will measure the immune responses”.

Sumagen added that it “anticipates not only having the first HIV vaccine in market but also the eradication of HIV/AIDS for human beings”.

HIV/AIDS has killed 35 million people worldwide, and more than 34 million people currently live with the virus infection.

Since the virus was identified in 1983, there have been numerous trials through pharmaceutical companies and academic institutions around the world to develop vaccines; however, no vaccine has been successful to date.

Other HIV vaccines evaluated through human clinical trials have focused on either one specific component of HIV as an antigen, genetic vaccine using recombinant DNA, or recombinant viruses carrying the HIV genes.

Kang’s vaccine is unique in that it uses a killed whole HIV-1 (the most common of the two types of HIV), much like the killed whole virus vaccines for polio, influenza, rabies and hepatitis A. The HIV-1 is genetically engineered so it is safer and can be produced in large quantities.


Have you been threatened, hit, raped or had your property damaged or stolen because you are gay, lesbian, bisexual, transgender or intersex (LGBTI)? Then you have been a victim of a hate crime.
OUT offers exciting training to mainstream service providers and other interested parties. The training assists individuals to understand themselves as sexual beings.
Currently OUT distributes safer sex packs to a range of venues in Tshwane that are utilised by gay men and lesbian women. These packs also include responsible sex messaging, appropriate barrier methods and lube.
OUT's Engage Men’s Health project offers free and confidential sexual health services to gay, bisexual and other men who have sex with men (MSM).